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La Miel Aesthetics
Ariessence PDGF regenerative serum application during microneedling at La Miel Aesthetics medical spa in Raleigh, NC.

Regenerative

Ariessence PDGF, signal-grade regeneration.

Ariessence is a next-generation regenerative treatment built around PDGF, Platelet-Derived Growth Factor. It is applied topically after microneedling or in conjunction with other resurfacing treatments to accelerate healing and amplify collagen induction beyond what the body produces on its own. Unlike PRP and PRF, Ariessence is shelf-stable and bioengineered, so concentration is consistent every treatment and no blood draw is required.

  • Shelf-stable bioengineered serum
  • No blood draw required
  • Consistent PDGF concentration
  • Physician-supervised
  • Bilingual care

What this is

What PDGF is and why it matters

Your body uses growth factors to coordinate tissue repair. When skin is injured (by microneedling, lasers, or daily life), platelets release a cocktail of signaling proteins that tell nearby cells to rebuild. PDGF is one of the most important of those signals. It recruits fibroblasts to the injury site, triggers new collagen synthesis, and supports new blood vessel formation.

Ariessence is a standardized, sterile PDGF serum. Unlike PRP and PRF, which require drawing your own blood and centrifuging it for each session, Ariessence is a shelf-stable bioengineered product. That means consistent concentration every treatment, no blood draw, and no processing variability.

Because it is a topical growth factor (not an injectable), it layers cleanly with other procedures without adding significant downtime.

At La Miel

When we use Ariessence at La Miel

Ariessence is an amplifier. We pair it with procedures that create micro-channels or wound-healing signals so the PDGF can act where it is needed.

  • With microneedling

    The most common application. PDGF is applied topically during and after the microneedling session. Micro-channels allow growth factors to penetrate deeply. Excellent for acne scarring and fine lines.

    Suited for: Patients addressing acne scars, texture, or early fine lines.

  • Fractional laser recovery

    Applied immediately post-laser to accelerate healing and reduce downtime. Helps minimize redness and supports faster epithelial recovery.

    Suited for: Patients undergoing fractional resurfacing.

  • Under-eye rejuvenation (paired with PRF)

    Layered with PRF under-eye injections for dark circles and crepey texture. PRF provides broad growth factor mix; Ariessence concentrates the PDGF signal.

    Suited for: Patients with dark circles or under-eye texture concerns.

  • Hairline and scalp restoration

    Applied via scalp microneedling on a monthly protocol. Supports early-stage androgenetic alopecia and post-partum shedding. Results most visible at 3 to 4 months.

    Suited for: Early hair thinning, post-partum shedding.

Ready to start?

A consultation tells us what your skin needs. It takes under an hour.

What to expect

What to expect

  1. Consultation

    We confirm which paired procedure fits your concern (microneedling for texture, scalp protocol for hair, etc.).

  2. Treatment

    Standard protocol of the paired procedure plus Ariessence applied topically. 30 to 75 minutes total depending on the pairing.

  3. Recovery

    Pinkness for 24 hours; gentle skincare and SPF 50 for 7 days. No injection downtime.

  4. Series and maintenance

    3 to 4 sessions spaced 4 to 6 weeks apart for the initial series. Maintenance every 6 months.

Pricing

A note on pricing

Ariessence is priced as an add-on to the paired procedure. Standalone scalp protocols are quoted at consultation. Financing is available for full series.

View financing options

Common questions

Common questions about Ariessence

  • Ariessence is a shelf-stable bioengineered PDGF serum that delivers consistent regenerative signaling without requiring a blood draw the way PRF or PRP do. PRF and PRP are made from your own blood, which requires a draw and spin-down before each session. Ariessence is shelf-stable and bioengineered, so concentration is consistent every treatment, and no blood draw is required. All three are regenerative; they differ in source, consistency, and the specific growth factor profile.

Ready to book Ariessence PDGF?

Tell us what you would like to address. A consultation maps the right plan, the right product, and the right sequence for your skin.

Ready When You Are

Two ways to start: book the specific treatment you came for, or book a consultation and we will build your plan together.

Mon 10 to 8, Wed to Fri 10 to 5, Sat 9 to 2. Closed Tue and Sun.

7718 Six Forks Road, Suite 106, Raleigh, NC 27615