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La Miel Aesthetics
Xeomin purified neurotoxin treatment for wrinkles at La Miel Aesthetics medical spa in Raleigh, NC.

Tox Treatments

Xeomin, the naked neurotoxin.

Xeomin in Raleigh NC is the Merz Aesthetics neurotoxin, FDA-approved since 2010, and the only botulinum toxin type A on the market without accessory proteins. The "naked" formulation appeals to patients who have built tolerance to Botox over years of use, or who simply prefer the cleanest formulation available. Delivered by master-certified RN Adriana Sandoval under physician direction.

  • FDA-approved since 2010
  • No accessory proteins
  • MERZ Aesthetics rewards
  • Master-certified RN injector
  • Bilingual care

What this is

What makes Xeomin unique

Every botulinum toxin product on the market contains the same active 150 kDa neurotoxin protein. What differs is the accessory proteins packaged with it. Botox, Dysport, and Daxxify all carry accessory proteins. Xeomin does not.

Why does that matter clinically? For most patients, it does not. Onset, duration, and effect are comparable to Botox. But a subset of long-term Tox users develop antibodies to those accessory proteins over years of repeated dosing, gradually reducing how well their neurotoxin works. Switching to Xeomin removes the accessory proteins entirely, which can restore responsiveness.

For new Tox patients, Xeomin is a clean first option. For experienced patients who feel their Botox is not working like it used to, Xeomin is the most common alternative we recommend.

At La Miel

Where Xeomin fits at La Miel

Adriana selects Xeomin when patients want the purest formulation, when they suspect Botox tolerance, or when the Merz product line fits their existing rewards stack.

  • Glabellar 11s (primary FDA indication)

    Original FDA approval pathway. Smooths vertical lines between the brows with the same dose range as Botox.

    Suited for: Patients curious about the purified formulation.

  • Forehead and crow's feet (off-label)

    Standard upper-face treatment. Dosing converts cleanly from Botox at roughly 1 to 1.

    Suited for: Established Tox patients exploring alternatives.

  • Botox tolerance suspected

    When a long-term Botox patient reports diminishing effect despite consistent dose, switching to Xeomin removes accessory proteins from the equation and often restores responsiveness.

    Suited for: Patients with 5+ years of Botox use experiencing reduced effect.

  • Masseter and platysmal bands (off-label)

    Same indications as Botox for jaw slimming, TMJ, and neck banding. Dose ranges identical.

    Suited for: Patients who want the Merz product line for these areas.

Ready to start?

A consultation tells us what your skin needs. It takes under an hour.

What to expect

What to expect

  1. Consultation

    We discuss why you are considering Xeomin specifically and confirm candidacy.

  2. Treatment

    5 to 15 minutes of injections, identical patient experience to other neurotoxins.

  3. Onset

    Day 5 to 7 for first softening. Peak at 2 weeks. Slightly slower than Dysport, comparable to Botox.

  4. Duration

    3 to 4 months typical, similar to Botox.

Pricing

A note on pricing

Xeomin is priced per unit. Dosing converts 1 to 1 from Botox, so quote ranges look familiar if you have had Tox before. Every Xeomin treatment earns MERZ Aesthetics rewards, which stack with the other manufacturer programs we participate in.

View financing options

Common questions

Common questions about Xeomin

  • Xeomin is the only botulinum toxin available without accessory proteins, often called a purified or naked neurotoxin. Xeomin and Botox both contain the same active 150 kDa botulinum toxin type A protein. The difference is that Xeomin is delivered without the accessory proteins that Botox and Dysport carry. This "naked" formulation has identical clinical effect for most patients, but can be useful for patients who have built antibody-driven tolerance to other neurotoxins over years of use.

Ready to book Xeomin?

Tell us what you would like to address. A consultation maps the right plan, the right product, and the right sequence for your skin.

Ready When You Are

Two ways to start: book the specific treatment you came for, or book a consultation and we will build your plan together.

Mon 10 to 8, Wed to Fri 10 to 5, Sat 9 to 2. Closed Tue and Sun.

7718 Six Forks Road, Suite 106, Raleigh, NC 27615